Broncos vs 49ers
Final: Denver Broncos 14, San Francisco 49ers 24. Gridline had 49ers by 6.2 (right winner), and its side against the spread covered.
Sun Oct 4, 4:25 PM ET · Levi's Stadium · Week 4, 2026 NFL season
Pregame projection
| Gridline | Vegas | |
|---|---|---|
| Projected margin | 49ers by 6.2 | SF −3 |
| Total (Vegas + model adjustments) | 49.0 | 48.5 |
| Total (stats only) | 48.3 | |
| Win probability | 49ers 68% · Broncos 31% |
- Quarterbacks: Bo Nix (Broncos) vs Brock Purdy (49ers).
Questions
- How accurate is Gridline?
- Through Nov 12, Gridline has picked 91-45 straight up and 68-63 against the spread in 137 graded 2026 games, with total leans of 1.5+ points at 23-15.
More
- All Week 4 predictions
- Denver Broncos 2026 projections
- San Francisco 49ers 2026 projections
- Season board with live odds and the matchup calculator to change the QBs, weather or injuries
Projections are research, not betting advice. Sports betting is not legal in every state. If gambling stops being fun, call or text 1-800-GAMBLER.