49ers vs Chargers
Gridline projects the San Francisco 49ers to beat the Los Angeles Chargers 27-18 (75% to win). Vegas has no line posted.
Thu Dec 17, 8:15 PM ET · SoFi Stadium · Week 15, 2026 NFL season
Gridline vs Vegas
| Gridline | Vegas | |
|---|---|---|
| Projected margin | 49ers by 8.6 | no line posted |
| Total (Vegas + model adjustments) | 45.6 | — |
| Total (stats only) | 45.6 | |
| Win probability | Chargers 25% · 49ers 75% |
- Weather: indoors.
- Quarterbacks: Brock Purdy (49ers) vs Justin Herbert (Chargers).
Questions
- Who will win 49ers vs Chargers?
- Gridline projects the San Francisco 49ers to win 27-18, with a 75% chance to win outright.
- How accurate is Gridline?
- Through Nov 12, Gridline has picked 91-45 straight up and 68-63 against the spread in 137 graded 2026 games, with total leans of 1.5+ points at 23-15.
More
- All Week 15 predictions
- San Francisco 49ers 2026 projections
- Los Angeles Chargers 2026 projections
- Season board with live odds and the matchup calculator to change the QBs, weather or injuries
Projections are research, not betting advice. Sports betting is not legal in every state. If gambling stops being fun, call or text 1-800-GAMBLER.