49ers vs Rams
Final: San Francisco 49ers 27, Los Angeles Rams 7. Gridline had Rams by 4.2 (wrong winner), and its side against the spread did not cover.
Thu Sep 10, 8:35 PM ET · Melbourne Cricket Ground · Week 1, 2026 NFL season
Pregame projection
| Gridline | Vegas | |
|---|---|---|
| Projected margin | Rams by 4.2 | LA −3.5 |
| Total (Vegas + model adjustments) | 47.7 | 47.5 |
| Total (stats only) | 52.9 | |
| Win probability | Rams 63% · 49ers 37% |
- Quarterbacks: Brock Purdy (49ers) vs Matthew Stafford (Rams).
Questions
- How accurate is Gridline?
- Through Nov 12, Gridline has picked 91-45 straight up and 68-63 against the spread in 137 graded 2026 games, with total leans of 1.5+ points at 23-15.
More
- All Week 1 predictions
- San Francisco 49ers 2026 projections
- Los Angeles Rams 2026 projections
- Season board with live odds and the matchup calculator to change the QBs, weather or injuries
Projections are research, not betting advice. Sports betting is not legal in every state. If gambling stops being fun, call or text 1-800-GAMBLER.